With vaccines rolling out more widely in the United States and daily new COVID-19 cases getting progressively lower, San Diego Comic-Con has been scheduled as an in-person event for later this year. However, the organizers opted to do it on Thanksgiving weekend, and unless you live locally, attending would mean missing Thanksgiving itself.
Comic-Con Special Edition will take place at the San Diego Convention Center as a three-day event from November 26 through November 28. That means it starts the day after Thanksgiving, assuming the health situation allows for it.